Considering that SARMS are illegal for consumption and WADA is going all-guns-blasting against it, the only legal, legitimate PED that you can get your hands on is Ibutamoren.
This orally active, potent GH secretagogue is a very powerful compound that can be used long term (6-12 months) without the fear of toxic side effects.
It requires no PCT and does not affect your HPTA or sexual hormones.
Sounds like a dream drug.
But is the right compound for everyone?
More importantly, what results can you get if you are willing to pay the price of Ibutamoren for a year, which isn’t cheap by the way.
Let’s talk about Ibutamoren and how to maximize the results with this Ghrelin mimetic.
History of Ibutamoren
Ibutamoren or Nutrobal, also known under the investigational drug names MK-677 & MK-0677 is a GH secretagogue. This means that it stimulates the pituitary gland into releasing Growth hormone in the body, along with IGF-1.
Two hormones that form the bedrock of anabolism and overall wellbeing.
Unlike synthetic GH which needs to be pinned and refrigerated to prevent it from deteriorating, Ibutamoren has excellent oral bioavailability and an extended shelf life at normal room temperature.
This means that you can just squeeze out a couple of drops under the tongue every day and get the full benefits.
It is being considered as a cheaper and safer alternative for exogenous growth hormone for the treatment of conditions like GH deficiency, Osteoporosis and age-related weakness in the elderly.
So far, the results are very positive and the general consensus in the medical community is that Ibutamoren will probably replace exogenous GH in the years to come.
Clinical studies of MK-677
Multiple clinical studies have been conducted in the past decade to analyze the efficiency and safety of Ibutamoren.
Here are some links.
Changes in body composition and energy expenditure were of an anabolic nature, with a sustained increase in FFM and a transient increase in BMR.J Clin Endocrinol Metab. 1998 Feb;83(2):362-9.
What it says: MK-677 when administered in obese men helps increase the levels of GH, IGF-I, and IGF-binding protein consistently over two months. There were no major adverse effects. The men were able to gain fat-free lean muscle mass and their basal metabolic rate increased, which means they were able to burn fat while building muscle.
What it says: Dosing just once a day with MK-677 increases bone density and strength in elderly men and women.
What it says: MK-677 restores the amplitude of natural GH in the body of aging men to the levels of much younger men. The results are not purely physical either. This also helps prevent cognitive decline and may help reducing dependency in conditions like Alzheimer’s disease.
What can you expect when you run an MK-677 cycle for 6-months or 12-months?
Let’s find out.
It is clinically proven that MK-677 not only increases lean muscle mass but it also helps the body burn fat in the process. In an 8-week study, test subjects were able to gain 6.6 lbs. of pure muscle on MK-677. But according to anecdotal reviews, the results are considered to be a tad slower. It might take 20-24 weeks at least before you start to notice the difference in the mirror. But you will get there. Also, the gains made with endogenous GH stimulation are believed by many to be permanent gains. You will keep the gains even when you go off the compound.
A lot of athletes take MK-677 purely for the nootropic benefits. The quality of sleep is incomparable. And the better you rest, the faster you recover. A caveat is that you get some crazy dreams. But we haven’t seen anyone complaining about it.
MK-677 increases basal metabolic rate or BMR in obese men. When clubbed with the increase in lean muscle mass, most people are able to lose fat without losing too much weight on the scale. Think about retaining all your muscle and losing body fat even when you are in a calorie deficit. This makes MK-677 one of the best compounds for body recomposition cycles.
MK-677 boosts your immunity, is said to improve the quality of skin (anecdotal only) and also improves the rate of hair growth. That’s one of the reasons why steroid users often hop on to Nutrobal in between cycles. It helps restore and recover some of the damage that the harsh compounds do to their bodies during the cycle.
Side Effects of Ibutamoren
Despite being a relatively safe compound, the continual increase in GH and IGF-1 are bound to have some repercussions. However, most of the side effects can be controlled by using ancillaries.
Reduced insulin sensitivity:
In one of the clinical studies, it was revealed that MK677 reduces insulin sensitivity and increases blood sugar levels. However, the degree to which it reduces insulin sensitivity is not even close to cause Diabetes. So, if you read somewhere that Nutrobal can cause diabetes, take it with a pinch of salt. You can supplement with Berberine to increase insulin sensitivity. Read up on the side effects of Berberine before you add it to your regime.
This one is real though. MK677 is a ghrelin mimetic. In simpler terms, it is an appetite stimulant and a notorious one at that. A lot of people use stimulants or appetite suppressants in the initial stages of using Ibutamoren as the hunger pangs can make it impossible to function normally. An easy work around? Use Nutrobal to bulk. It will make you eat like a horse.
Increased IGF and GH can cause water retention. If you are experiencing edema in the hands or legs, then chances are that your blood pressure levels might have also spiked. Monitor the levels frequently while you are on Nutrobal.
Ibutamoren vs. GH
Much before MK-677 was available as commonly as it is today, bodybuilders had to rely on expensive GH injections sourced from UG labs.
Not only are the sources dubious, the injections are ridiculously expensive. Think approximately $1000 for a weekly supply of GH. Run the math for a yearly supply.
Not affordable. MK-677 on the other hand amplifies endogenous GH and keeps the IGF-1 levels boosted for up to 24-hours after you take the dose.
That’s as good as a low dose of exogenous GH at less than 10% of the cost.
You have the answer, loud and clear. MK-677 any day.